Safety Data Sheets (SDSs) are designed to provide workers and emergency personnel with important safety information to ensure safe handling of hazardous chemicals and appropriate spill response.
2. Chemicals developed in a laboratory and sent to another laboratory are required
to have an SDS and it must be sent with the chemical containers to the next user (OSHA
interpretation letter dated 2/5/04). 4. Chemicals that are considered "Hazardous Drugs" must be handled using the OSHA
"Controlling Occupational Exposure to Hazardous Drugs" guidelines (OSHA Technical
Manual, Sect. VI, Chap. 2). Hazardous drugs are defined as genotoxic, carcinogenic,
teratogenic or reproductive hazard, or cause serious organ or other toxic manifestation
at low doses in experimental animals or treated patients. If a drug is designated
(or being developed to be designated) as an antineoplastic agent, it is considered
a hazardous drug. 2. Use OSHA short form or ANSI format. Use 16-Section SDS Checklist as a guide. Review
UN Annex 4 Guidance on the Preparation of Safety Data Sheets (SDS). OSHA will be adopting
this format in the near future under the Global Harmonization initiative.
3. Newly synthesized chemicals must comply with the EPA TSCA requirements (40 CFR
700-799). There are exemptions for research and development (EPA Bulletin 1986-1,
40 CFR 720.36). This exemption can be partially met by including a statement on the
MSDS (see EH&S memo 6/15/00 and EMD SDS): "This product is being sent to you as a
Research and Development product as defined by the Toxic Substances Control Act (TSCA)
of 1976. Due to TSCA's R&D exemption, this product is not listed on the U.S. EPA's
Toxic Substances Control Act inventory. As a TSCA-exempt R&D substance, this product
must be used by or directly under the supervision of a technically qualified individual(s)
as defined by TSCA. This product may not be used for commercial purposes or in formulations
used for commercial purposes."
Other requirements are:
Steps to writing an SDS
1. Review OSHA requirements (29 CFR 1910.1200; Guidance for Hazard Determination).
3. Review Sigma or other manufacturer's SDSs for similar products.
4. Use established Risk and Safety Statements (see Sigma printout).
5. Include TSCA R&D exemption wording.
IMPORTANT NOTE: These instructions are for chemicals and products distributed within
the USA only! Other countries have different SDS requirements (EU REACH). The SDS
must be in the native language of the country the chemical or product is sent to.

BIOLOGICAL SAFETY OFFICER
Chris Kuhlow | (631) 632-3717 | Christopher.Kuhlow@stonybrook.edu

CHEMICAL HYGIENE OFFICER
Ying Liu | (631) 632-3032 | Ying.Liu.1@stonybrook.edu
